Cadiot-Chodkiewicz Coupling

The Copper(I)-catalyzed Coupling Of A Terminal Alkyne And An Alkynyl Halide Offers Access To Unsymmetrical Bisacetylenes.

Mechanism Of The Cadiot-Chodkiewicz Coupling

Recent Literature

Copper(I) Iodide Catalyzed Cross-Coupling Reaction Of Terminal Alkynes With 1-Bromoalkynes: A Simple Synthesis Of Unsymmetrical Buta-1,3-diynes
S. Wang, L. Yu, P. Li, L. Meng, L. Wang, Synthesis, 2011, 1541-1546.

Synthesis Of 1,3-Diynes Via Cadiot-Chodkiewicz Coupling Of Volatile, In Situ Generated Bromoalkynes
P. C. Knutson, H. E. Fredericks, E. M. Ferreira, Org. Lett., 2018, 20, 6845-6849.

Bulky Trialkylsilyl Acetylenes In The Cadiot-Chodkiewicz Cross-Coupling Reaction
J. P. Marino, H. N. Nguyen, J. Org. Chem., 2002, 67, 6841-6844.

End-Cap Stabilized Oligoynes: Model Compounds For The Linear Sp Carbon Allotrope Carbyne
T. Gibtner, F. Hampel, J.-P.Gisselbrecht, A. Hirsch, Chem. Eur. J., 2002, 68, 408-432.