Fischer Indole Synthesis

The Conversion Of Aryl Hydrazones To Indoles; Requires Elevated Temperatures And The Addition Of Brønsted Or Lewis Acids. Some Interesting Enhancements Have Been Published Recently; For Example A Milder Conversion When N-trifluoroacetyl Enehydrazines Are Used As Substrates. (abstract).

Mechanism Of The Fischer Indole Synthesis

Recent Literature

Aryl Hydrazide Beyond As Surrogate Of Aryl Hydrazine In The Fischer Indolization: The Synthesis Of N-Cbz-indoles, N-Cbz-carbazoles, And N,N'-Bis-Cbz-pyrrolo[2,3-f]indoles
I.-K. Park, S.-E. Suh, B.-Y. Lim, C.-G. Cho, Org. Lett., 2009, 11, 5454-5456.

Fischer Indole Synthesis In Low Melting Mixtures
S. Gore, S. Baskaran, B. König, Org. Lett., 2012, 14, 4568-4571.

From Alcohols To Indoles: A Tandem Ru Catalyzed Hydrogen-Transfer Fischer Indole Synthesis
A. Porcheddu, M. G. Mura, L. De Luca, M. Pizzetti, M. Taddei, Org. Lett., 2012, 14, 6112-6115.

Three- And Four-Component Syntheses Of 3-Arylmethylindoles By Microwave-Assisted One-Pot Heck Isomerization-Fischer Indolization (Alkylation) (HIFI And HIFIA) Sequences
J. Panther, T. J. J. Müller, Synthesis, 2016, 48, 974-986.

Efficient Preparation Of Polyfunctional Indoles Via A Zinc Organometallic Variation Of The Fischer Indole Synthesis
Z..-G. Zhang, B. A. Haag, J.-S. Li, P. Knochel, Synthesis, 2011, 23-29.

A Palladium-Catalyzed Strategy For The Preparation Of Indoles: A Novel Entry Into The Fischer Indole Synthesis
S. Wagaw, B. H. Yang, S. L. Buchwald, J. Am. Chem. Soc., 1998, 120, 6621-6622.

The Benzyne Fischer-Indole Reaction
D. McAusland, S. Seo, D. G. Pintori, J. Finlayson, M. F. Greaney, Org. Lett., 2011, 13, 3667-3669.

Thermal Cyclization Of N-trifluoracetyl Enehydrazines Under Mild Conditions: A Novel Entry Into The Fischer Indole Synthesis
O. Miyata, Y. Kimura, K. Muroya, H. Hiramatsu, T. Naito, Tetrahedron Lett., 1999, 40, 3601-3604.