Tebbe Olefination

Tebbe Olefination

The Tebbe Reagent Is A Metal Carbenoid Prepared From The Dimetallomethylene Species Derived By The Reaction Of Trimethyl Aluminium With Titanocene Dichloride; This Reagent Exhibits Carbenoid Behaviour After The Addition Of A Catalytic Amount Of Pyridine. The Tebbe Reagent Reacts With Various Carbonyl Partners To Give The Product Of Methylenation:

Aldehydes To Alkenes

Ketones To Alkenes

Esters To Enol Ethers

Amides To Enamines


Mechanism Of The Tebbe Olefination