This Reaction Sequence Allows The Preparation Of Aziridines From 1,2-amino Alcohols.
After Preparation Of Sulphonate Salt, A Second Deprotonation Step Effects The Ring Closure:
Recent Literature
An Improved And Mild Wenker Synthesis Of Aziridines
X. Li, N. Chen, J. Xu, Synthesis, 2010, 3315-3318.
Synthesis Of N-H Vinylaziridines: A Comparative Study
B. Olofsson, R. Wijtmans, P. Somfai, Tetrahedron, 2002, 58, 5979-5982.
Short And Efficient Synthesis Of Optically Active N-Tosyl Aziridines From 2-Amino Alcohols
L. W. Bieber, M. C. F. De Araujo, Molecules, 2002, 7, 902.
Generation And Ring Opening Of Aziridines In Telescoped Continuous Flow Processes
N. Hsueh, G. J. Clarkson, M. Shipman, Org. Lett., 2015, 17, 3632-3635.